Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.44 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | S100B | P04271 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031211 | 0.80 | F10 (0.48) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL8174692 | 0.75 | F2 (0.42) | PRSS1PRSS2PRSS3TMPRSS2F2 | |
| SCHEMBL9030472 | 0.74 | PRSS1 (0.41) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL9030444 | 0.74 | PRSS1 (0.48) | PRSS1PRSS2PRSS3TMPRSS2PRMT1 | |
| SCHEMBL8555997 | 0.73 | PRSS1 (0.47) | PRSS1PRSS2PRSS3F2F10 | |
| SCHEMBL9030918 | 0.71 | F2 (0.43) | PRSS1PRSS2PRSS3F2ST14 | |
| SCHEMBL16450841 | 0.70 | PRSS1 (0.62) | PRSS1PRSS2PRSS3TMPRSS2PRMT1 | |
| SCHEMBL9029684 | 0.70 | PRSS1 (0.37) | PRSS1PRSS2PRSS3TMPRSS2PRMT1 | |
| SCHEMBL12461919 | 0.70 | PRSS1 (0.48) | PRSS1PRSS2PRSS3TMPRSS2PRMT1 | |
| SCHEMBL9647355 | 0.70 | PRSS1 (0.78) | PRSS1PRSS2PRSS3TMPRSS2PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |