Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 11/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 3/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | C1S | P09871 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8193455 | 0.81 | LMNA (0.45) | F10LOXL2 | |
| SCHEMBL8852497 | 0.81 | TSHR (0.48) | — | |
| SCHEMBL8556448 | 0.80 | ALDH1A1 (0.61) | F10PRSS1PRSS2PRSS3LOXL2 | |
| SCHEMBL13948677 | 0.79 | KMT2A (0.48) | — | |
| SCHEMBL18945510 | 0.78 | EPHX2 (0.46) | — | |
| SCHEMBL2309460 | 0.78 | EPHX2 (0.46) | — | |
| SCHEMBL27484985 | 0.77 | ALDH1A1 (0.56) | — | |
| SCHEMBL21540041 | 0.77 | L3MBTL1 (0.53) | — | |
| SCHEMBL456516 | 0.77 | ALDH1A1 (0.59) | — | |
| SCHEMBL13813622 | 0.76 | PRSS1 (0.81) | PRSS1PRSS2PRSS3F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |