Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 4/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9281848 | 0.88 | MAPT (0.37) | CTSBARPKMSMN1; SMN2MAPT | |
| SCHEMBL8555066 | 0.88 | CTSB (0.45) | CTSBARPKMSMN1; SMN2MAPT | |
| SCHEMBL8967939 | 0.85 | KAT2B (0.50) | PKMSMN1; SMN2MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL8968053 | 0.84 | KAT2B (0.51) | PKMSMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL8553639 | 0.81 | TDP1 (0.44) | CTSBARSMN1; SMN2MAPTLMNA | |
| SCHEMBL8967549 | 0.79 | MAPT (0.43) | PKMSMN1; SMN2MAPTLMNAKMT2A | |
| Fumaric Acid SCHEMBL8968115 | 0.78 | NPC1 (0.43) | PKMSMN1; SMN2MAPTLMNAKMT2A | |
| Maleic Acid SCHEMBL8967637 | 0.78 | NPC1 (0.43) | PKMSMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL8555094 | 0.77 | HRH3 (0.38) | PKMSMN1; SMN2MAPTKMT2AHRH3 | |
| SCHEMBL8967649 | 0.76 | CA12 (0.49) | SMN1; SMN2MAPTKMT2AHRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | claimed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | claimed |
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0543307-A2 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |