Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 4/20 | 0.51 |
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8557858 | 0.98 | CACNA1G (0.49) | CACNA1GKDRMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8552139 | 0.89 | CACNA1G (0.49) | CACNA1GMEN1KMT2AALDH1A1ADRB1 | |
| SCHEMBL8556935 | 0.78 | ALDH1A1 (0.48) | KDRMEN1KMT2AALDH1A1ADRB1 | |
| SCHEMBL8552887 | 0.78 | NR4A2 (0.47) | KDRMEN1KMT2AALDH1A1ADRB1 | |
| SCHEMBL6277857 | 0.77 | MEN1 (0.65) | MEN1KMT2AALDH1A1LMNATSHR | |
| SCHEMBL2327539 | 0.76 | ALDH1A1 (0.64) | MEN1KMT2AALDH1A1ADRB1CYP3A4 | |
| SCHEMBL20419773 | 0.75 | EGLN1 (0.48) | MEN1KMT2AALDH1A1DRD3DRD2 | |
| SCHEMBL18409495 | 0.74 | KDM4E (0.52) | MEN1KMT2AALDH1A1KCNH2LMNA | |
| SCHEMBL18409353 | 0.74 | MEN1 (0.54) | MEN1KMT2AALDH1A1CYP2D6DRD3 | |
| SCHEMBL8556384 | 0.74 | MEN1 (0.60) | MEN1KMT2AALDH1A1ADRB1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | claimed |
| US-5382584-A | Antiischemic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-01-17 | — | — | US | claimed |
| EP-0582164-A1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | Bristol-Myers Squibb Company (US) | 1994-02-09 | — | — | EP | claimed |