Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552910 | 0.88 | LMNA (0.50) | ALDH1A1TSHRNPC1CLK1RAB9A | |
| SCHEMBL8552887 | 0.80 | NR4A2 (0.47) | ALDH1A1TSHRMEN1KMT2AKDR | |
| SCHEMBL6277857 | 0.79 | MEN1 (0.65) | ALDH1A1TSHRMEN1KMT2ALMNA | |
| SCHEMBL8556067 | 0.78 | CACNA1G (0.51) | ALDH1A1TSHRMEN1KMT2AKDR | |
| Hydrochloric Acid SCHEMBL8557858 | 0.77 | CACNA1G (0.49) | ALDH1A1TSHRMEN1KMT2AKDR | |
| SCHEMBL2327539 | 0.76 | ALDH1A1 (0.64) | ALDH1A1TSHRMEN1KMT2ALMNA | |
| SCHEMBL8556384 | 0.74 | MEN1 (0.60) | ALDH1A1TSHRMEN1KMT2ALMNA | |
| SCHEMBL8555057 | 0.73 | NR4A2 (0.51) | TSHRMEN1KMT2ALMNAADRB1 | |
| SCHEMBL8557576 | 0.72 | MEN1 (0.52) | ALDH1A1TSHRMEN1KMT2ALMNA | |
| SCHEMBL6261397 | 0.71 | ALOX15 (0.74) | ALDH1A1TSHRMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | claimed |
| US-5382584-A | Antiischemic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-01-17 | — | — | US | claimed |
| EP-0582164-A1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | Bristol-Myers Squibb Company (US) | 1994-02-09 | — | — | EP | claimed |