Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CPA1 | P15085 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552112 | 1.00 | MAOB (0.48) | MAOBNPC1RAB9AALDH1A1GAA | |
| SCHEMBL16329903 | 0.81 | MAOB (0.52) | MAOBALDH1A1MAPTTP53CA1 | |
| SCHEMBL29185811 | 0.81 | MAOB (0.43) | MAOBNPC1RAB9ATP53CA1 | |
| SCHEMBL9077527 | 0.78 | ALDH1A1 (0.41) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL9077524 | 0.78 | ALDH1A1 (0.41) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL9077521 | 0.78 | ALDH1A1 (0.41) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL5674577 | 0.77 | MAOB (0.43) | MAOBNPC1RAB9AALDH1A1TP53 | |
| SCHEMBL6978584 | 0.77 | CHRNB2 (0.46) | ALDH1A1TDP1 | |
| SCHEMBL8556130 | 0.77 | TAAR1 (0.43) | MAOBNPC1RAB9AALDH1A1IDO1 | |
| SCHEMBL8556127 | 0.77 | TAAR1 (0.43) | MAOBNPC1RAB9AALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626951-B1 | BENZISOXAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BRITISH TECH GROUP (GB) | 1998-07-29 | — | — | EP | disclosed |
| US-5578626-A | Pharmaceutical compositions | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-11-26 | — | — | US | disclosed |
| US-5476867-A | Pharmaceutical compositions | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-12-19 | — | — | US | disclosed |
| EP-0626951-A1 | BENZISOXAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BTG INTERNATIONAL LIMITED (GB) | 1994-12-07 | — | — | EP | disclosed |
| WO-1993017004-A1 | BENZISOXAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1993-09-02 | — | — | WO | disclosed |