Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554553 | 0.82 | PTGS2 (0.66) | PTGS1PTGS2GAALMNAL3MBTL1 | |
| SCHEMBL8556342 | 0.81 | PTGS2 (0.72) | PTGS1PTGS2FBP1LMNAKMT2A | |
| SCHEMBL8552699 | 0.81 | PTGS1 (0.55) | PTGS1PTGS2GAAFBP1LMNA | |
| SCHEMBL8554620 | 0.79 | PTGS1 (0.52) | PTGS1PTGS2FBP1LMNAKMT2A | |
| SCHEMBL8554850 | 0.79 | PTGS2 (0.53) | PTGS1PTGS2FBP1LMNAKMT2A | |
| SCHEMBL8557299 | 0.79 | PTGS1 (0.53) | PTGS1PTGS2GAAFBP1LMNA | |
| SCHEMBL8555161 | 0.79 | PTGS2 (0.53) | PTGS1PTGS2FBP1LMNAKMT2A | |
| SCHEMBL8550834 | 0.77 | PTGS2 (0.66) | PTGS1PTGS2MAPTLMNAALDH1A1 | |
| SCHEMBL8553129 | 0.77 | PTGS2 (0.66) | PTGS1PTGS2CYP2C9FBP1LMNA | |
| SCHEMBL8552523 | 0.77 | PTGS2 (0.66) | PTGS1PTGS2FBP1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |