Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.66 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | FPR1 | P21462 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556342 | 0.95 | PTGS2 (0.72) | PTGS2PTGS1FBP1FPR1LMNA | |
| SCHEMBL8550834 | 0.90 | PTGS2 (0.66) | PTGS2PTGS1FPR1EGFRERBB2 | |
| SCHEMBL8552523 | 0.90 | PTGS2 (0.66) | PTGS2PTGS1FBP1FPR1LMNA | |
| SCHEMBL8554553 | 0.90 | PTGS2 (0.66) | PTGS2PTGS1FPR1LMNAGFER | |
| SCHEMBL8551988 | 0.88 | PTGS2 (0.73) | PTGS2PTGS1FPR1LMNASMN1; SMN2 | |
| SCHEMBL8559075 | 0.87 | PTGS2 (0.63) | PTGS2PTGS1FPR1LMNAALDH1A1 | |
| SCHEMBL8552699 | 0.82 | PTGS1 (0.55) | PTGS2PTGS1FBP1FPR1LMNA | |
| SCHEMBL8551424 | 0.82 | PTGS1 (0.65) | PTGS2PTGS1FPR1GFER | |
| SCHEMBL8554538 | 0.82 | PTGS1 (0.54) | PTGS2PTGS1FBP1LMNAALDH1A1 | |
| SCHEMBL8557299 | 0.80 | PTGS1 (0.53) | PTGS2PTGS1FBP1FPR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |