Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | FPR1 | P21462 | 7/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556342 | 0.95 | PTGS2 (0.72) | PTGS2PTGS1LMNAGFERFPR1 | |
| SCHEMBL8551424 | 0.92 | PTGS1 (0.65) | PTGS2PTGS1GFERFPR1GAA | |
| SCHEMBL8550834 | 0.90 | PTGS2 (0.66) | PTGS2PTGS1LMNAFPR1 | |
| SCHEMBL8553129 | 0.90 | PTGS2 (0.66) | PTGS2PTGS1LMNAGFERFPR1 | |
| SCHEMBL8552523 | 0.90 | PTGS2 (0.66) | PTGS2PTGS1LMNAGFERFPR1 | |
| SCHEMBL8554524 | 0.90 | PTGS1 (0.62) | PTGS2PTGS1LMNAGFER | |
| SCHEMBL8552452 | 0.90 | PTGS1 (0.62) | PTGS2PTGS1GFERGAAL3MBTL1 | |
| SCHEMBL8553948 | 0.89 | PTGS1 (0.62) | PTGS2PTGS1LMNAGFERFPR1 | |
| SCHEMBL8551988 | 0.88 | PTGS2 (0.73) | PTGS2PTGS1LMNAFPR1 | |
| SCHEMBL8552699 | 0.88 | PTGS1 (0.55) | PTGS2PTGS1LMNAFPR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |