SCHEMBL8556341

SCHEMBL8556341

CN(C)C(=Cc1ccccc1)N(C)C

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TSHR P16473 1/20 0.46
AKR1C3 P42330 1/20 0.46
FBP1 P09467 2/20 0.42
RELA Q04206 1/20 0.41
CYP2D6 P10635 1/20 0.41
AKR1C1 Q04828 1/20 0.40
ESR1 P03372 1/20 0.40
KDM1A O60341 1/20 0.39
RECQL P46063 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPT P10636 2/20 0.39
NISCH Q9Y2I1 1/20 0.39
HTT P42858 1/20 0.38
MAPK1 P28482 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1123661 0.83 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3FBP1RELA
SCHEMBL7723075 0.80 ALDH1A1 (0.46) ALDH1A1TSHRAKR1C3FBP1RELA
SCHEMBL8639781 0.76 ALDH1A1 (0.43) ALDH1A1TSHRAKR1C3FBP1RELA
SCHEMBL2845203 0.75 AKR1C1 (0.45) ALDH1A1TSHRAKR1C3CYP2D6AKR1C1
SCHEMBL7904469 0.75 ESR1 (0.45) ALDH1A1TSHRAKR1C3RELACYP2D6
SCHEMBL6426745 0.73 MEN1 (0.56) ALDH1A1RELACYP2D6MEN1KMT2A
SCHEMBL9155729 0.73 FBP1 (0.41) ALDH1A1TSHRAKR1C3FBP1RELA
SCHEMBL1629563 0.73 AKR1C3 (0.50) ALDH1A1TSHRAKR1C3FBP1AKR1C1
SCHEMBL11139540 0.73 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3FBP1AKR1C1
SCHEMBL8824100 0.73 ALDH1A1 (0.55) ALDH1A1TSHRAKR1C3FBP1RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0598503-B1 Magnetic recording materials MINNESOTA MINING & MFG (US) 1998-12-09 EP disclosed
US-5462823-A Containing an infrared absorbing dye MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-10-31 US disclosed
EP-0598503-A2 Magnetic recording materials MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-05-25 EP disclosed
US-4719245-A TRIMERIZATION CATALYST THE DOW CHEMICAL COMPANY (US) 1988-01-12 US disclosed
US-4703099-A CATALYTICALLY TRIMERIZING ISOCYANATES THE DOW CHEMICAL COMPANY (US) 1987-10-27 US disclosed
US-4632989-A KETENE AMINAL-OLEFIN REACTION PRODUCT AS CATALYSTS THE DOW CHEMICAL COMPANY (US) 1986-12-30 US disclosed
US-4536490-A REACTION PRODUCT OF KETENE-AMINAL AND UNSATURATED COMPOUND THE UPJOHN COMPANY (US) 1985-08-20 US disclosed