SCHEMBL2845203

SCHEMBL2845203

CN(C)C(=Cc1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.45
CYP2D6 P10635 1/20 0.45
ALDH1A1 P00352 4/20 0.45
MAPT P10636 3/20 0.45
MTNR1A P48039 2/20 0.43
MTNR1B P49286 2/20 0.43
MAPK1 P28482 1/20 0.42
RAB9A P51151 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TSHR P16473 1/20 0.42
AKR1C3 P42330 1/20 0.42
PRMT1 Q99873 1/20 0.41
ESR1 P03372 1/20 0.41
KMT2A Q03164 2/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
RECQL P46063 1/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7904469 0.96 ESR1 (0.45) AKR1C1CYP2D6ALDH1A1MAPTMTNR1A
SCHEMBL4199808 0.88 ESR1 (0.58) CYP2D6MAPTESR1KMT2AMEN1
SCHEMBL305384 0.87 CYP19A1 (0.50) CYP2D6ALDH1A1MAPTMAPK1KMT2A
Hydrochloric Acid SCHEMBL9803951 0.85 CYP19A1 (0.49) CYP2D6ALDH1A1MAPTMAPK1KMT2A
SCHEMBL7944757 0.85 ALDH1A1 (0.48) AKR1C1CYP2D6ALDH1A1MAPTTSHR
SCHEMBL12411237 0.82 KMT2A (0.47) AKR1C1CYP2D6ALDH1A1MAPTMTNR1A
SCHEMBL2992588 0.81 LCK (0.41) AKR1C1ALDH1A1MAPTMAPK1RAB9A
SCHEMBL2992590 0.81 LCK (0.41) AKR1C1ALDH1A1MAPTMAPK1RAB9A
SCHEMBL2992596 0.80 MAPT (0.39) ALDH1A1MAPTRAB9ALMNAGAA
SCHEMBL27808829 0.80 CYP1B1 (0.47) ALDH1A1MAPTMAPK1AKR1C3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 388 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3262055-B1 WATER SOLUBLE FLUORESCENT OR COLORED DYES COMPRISING CONJUGATING GROUPS SONY GROUP CORP (JP) 2026-04-22 EP claimed
EP-4137818-B1 USE OF DIVALENT METALS FOR ENHANCEMENT OF FLUORESCENT SIGNALS SONY GROUP CORP (JP) 2025-12-10 EP claimed
EP-3440136-B1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY GROUP CORP (JP) 2025-07-23 EP claimed
US-12359071-B2 Polymeric tandem dyes with linker groups Sony Group Corporation (JP) 2025-07-15 US claimed
WO-2025047293-A1 COMPOUND, DETECTION SYSTEM, AND MEASUREMENT DEVICE ソニーグループ株式会社 2025-03-06 WO claimed
US-20250009898-A1 PYRROLOBENZODIAZEPINE CONJUGATES FOR CANCER TREATMENT SONY GROUP CORP (JP) 2025-01-09 US claimed
US-20250009786-A1 AUTOMATED SYNTHESIS OF POLYMERIC DUAL DRUGS Sony Group Corporation (JP) 2025-01-09 US claimed
US-20240294767-A1 POLYMERIC TANDEM DYES WITH LINKER GROUPS SONY GROUP CORP (JP) 2024-09-05 US claimed
EP-4408473-A1 AUTOMATED SYNTHESIS OF POLYMERIC DUAL DRUGS Sony Group Corporation (JP) 2024-08-07 EP claimed
US-20240210408-A1 USE OF DIVALENT METALS FOR ENHANCEMENT OF FLUORESCENT SIGNALS SONY GROUP CORP (JP) 2024-06-27 US claimed
US-7423133-B2 Fluorescent glycosides and methods for their use THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2008-09-09 US claimed
US-20040215012-A1 FLUORESCENT GLYCOSIDES AND METHODS FOR THEIR USE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2004-10-28 US claimed
WO-2004019002-A2 FLUORESCENT GLYCOSIDES AND METHODS FOR THEIR USE THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2004-03-04 WO claimed
US-6670193-B2 Coupling with organometallic compound; emission light RESEARCH CORPORATION TECHNOLOGIES, INC. 2003-12-30 US claimed
US-6479650-B1 Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same RESEARCH CORPORATION TECHNOLOGIES, INC. 2002-11-12 US claimed
US-20020160411-A1 Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 2002-10-31 US claimed
WO-2001044220-A2 FLUORESCENT NUCLEOSIDE ANALOGS AND COMBINATORIAL FLUOROPHORE ARRAYS COMPRISING SAME RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 2001-06-21 WO claimed
EP-0026088-B1 PHOTORESIST COMPOSITIONS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-11-23 EP claimed
US-4349619-A CONTAINING ANTIHALATION AGENTS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-09-14 US claimed
EP-0026088-A2 Photoresist compositions JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-04-01 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020160411-A1 Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same DERA, FBL, DUT AKR1C1 1780/4885CYP2D6 1525/4885ALDH1A1 1698/4885
US-12359071-B2 Polymeric tandem dyes with linker groups CHRM1, IK, TMT1A AKR1C1 1436/4885CYP2D6 3656/4885ALDH1A1 1531/4885
US-20250009898-A1 PYRROLOBENZODIAZEPINE CONJUGATES FOR CANCER TREATMENT CHRM1, TPD52L2, H1-3 AKR1C1 3605/4885CYP2D6 496/4885ALDH1A1 1901/4885
US-20250009786-A1 AUTOMATED SYNTHESIS OF POLYMERIC DUAL DRUGS CHRM1, CHRM2, H1-0 AKR1C1 2990/4885CYP2D6 196/4885ALDH1A1 1723/4885
US-20240294767-A1 POLYMERIC TANDEM DYES WITH LINKER GROUPS CHRM1, IK, TMT1A AKR1C1 1436/4885CYP2D6 3656/4885ALDH1A1 1531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.