Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.41 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555033 | 0.82 | MAPT (0.43) | SIRT1TP53EGFRAKT1AKT2 | |
| SCHEMBL8554779 | 0.82 | TP53 (0.37) | SIRT1TP53EGFRAKT1AKT2 | |
| SCHEMBL8554723 | 0.80 | TP53 (0.50) | SIRT1TP53EGFRAKT1AKT2 | |
| SCHEMBL8556432 | 0.77 | TP53 (0.47) | TP53EGFRAKT1AKT2AKT3 | |
| SCHEMBL8556548 | 0.77 | THRB (0.53) | TP53EGFRAKT1AKT2AKT3 | |
| SCHEMBL8556454 | 0.75 | TP53 (0.36) | TP53EGFRAKT1AKT2AKT3 | |
| SCHEMBL8554193 | 0.75 | TP53 (0.46) | TP53EGFRAKT1AKT2AKT3 | |
| SCHEMBL8557773 | 0.70 | POLB (0.48) | TP53MAPTNPC1RAB9AHPGD | |
| SCHEMBL11139020 | 0.66 | CSNK2A1 (0.66) | CYP1A1CYP1B1CSNK2A1MAPTKMT2A | |
| SCHEMBL5323814 | 0.64 | MAPT (0.54) | SIRT1TP53CYP1A1CYP1B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0554957-B1 | Thiazole derivatives of alkoxyacrylates with a fungicidal activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1998-04-15 | — | — | EP | disclosed |