Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 13/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TPH1 | P17752 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556961 | 0.87 | MAPT (0.45) | POLBRXFP1MRGPRX4TP53MAPT | |
| SCHEMBL8553136 | 0.82 | SMN1; SMN2 (0.41) | POLBRXFP1TP53MAPTHPGD | |
| SCHEMBL8553904 | 0.81 | THRB (0.40) | POLBTP53MAPTHPGDNPC1 | |
| SCHEMBL8556548 | 0.77 | THRB (0.53) | TP53MAPT | |
| SCHEMBL8556217 | 0.74 | MAPK9 (0.41) | TP53MAPT | |
| SCHEMBL8556456 | 0.71 | TP53 (0.36) | TP53MAPTHPGD | |
| SCHEMBL8556454 | 0.71 | TP53 (0.36) | TP53MAPTHPGD | |
| SCHEMBL8557547 | 0.70 | TP53 (0.51) | RXFP1TP53MAPTHPGDNPC1 | |
| SCHEMBL8557170 | 0.70 | TP53 (0.46) | POLBRXFP1TP53MAPTRAB9A | |
| SCHEMBL8556427 | 0.70 | SIRT1 (0.47) | POLBTP53MAPTHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0554957-B1 | Thiazole derivatives of alkoxyacrylates with a fungicidal activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1998-04-15 | — | — | EP | disclosed |
| US-5334609-A | Used in agriculture | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1994-08-02 | — | — | US | disclosed |
| EP-0554957-A2 | Thiazole derivatives of alkoxyacrylates with a fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1993-08-11 | — | — | EP | disclosed |