Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556548 | 0.76 | THRB (0.53) | THRBTP53MAPTEGFRAKT1 | |
| SCHEMBL3668984 | 0.74 | MAPT (0.59) | THRBTP53NPC1RAB9AMAPT | |
| SCHEMBL8554248 | 0.70 | MAPT (0.43) | THRBTP53MAPTKDM4EMEN1 | |
| SCHEMBL16399502 | 0.69 | GFER (0.57) | THRBTP53NPC1RAB9AL3MBTL1 | |
| SCHEMBL8553030 | 0.69 | THRB (0.42) | THRBTP53NPC1RAB9AMAPT | |
| Bromide SCHEMBL30852751 | 0.69 | MAPT (0.57) | THRBTP53NPC1RAB9AMAPT | |
| SCHEMBL8553036 | 0.69 | THRB (0.42) | THRBTP53NPC1RAB9AMAPT | |
| SCHEMBL8555297 | 0.68 | THRB (0.43) | THRBTP53MAPTABL1RXFP1 | |
| SCHEMBL9348088 | 0.68 | THRB (0.41) | THRBTP53NPC1RAB9ATDP1 | |
| SCHEMBL30852733 | 0.67 | MAPT (0.52) | THRBTP53NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0554957-B1 | Thiazole derivatives of alkoxyacrylates with a fungicidal activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1998-04-15 | — | — | EP | disclosed |
| EP-0554957-A2 | Thiazole derivatives of alkoxyacrylates with a fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1993-08-11 | — | — | EP | disclosed |