Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555297 | 0.90 | THRB (0.43) | MAPTTP53THRBRXFP1APP | |
| SCHEMBL8553036 | 0.86 | THRB (0.42) | MAPTTP53THRBKDM4EMEN1 | |
| SCHEMBL8553030 | 0.86 | THRB (0.42) | MAPTTP53THRBKDM4EMEN1 | |
| SCHEMBL8556548 | 0.73 | THRB (0.53) | MAPTTP53THRBAPP | |
| SCHEMBL8556775 | 0.73 | KDM4E (0.40) | MAPTTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL8556781 | 0.73 | KDM4E (0.40) | MAPTTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL3668984 | 0.70 | MAPT (0.59) | MAPTTP53THRBALDH1A1POLB | |
| SCHEMBL8556449 | 0.70 | THRB (0.53) | MAPTTP53THRBKDM4EMEN1 | |
| SCHEMBL27362934 | 0.69 | MAPT (0.59) | MAPTTP53KDM4EMEN1ALDH1A1 | |
| SCHEMBL27362937 | 0.67 | MAPT (0.59) | MAPTTP53MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0554957-B1 | Thiazole derivatives of alkoxyacrylates with a fungicidal activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1998-04-15 | — | — | EP | claimed |
| EP-0554957-A2 | Thiazole derivatives of alkoxyacrylates with a fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1993-08-11 | — | — | EP | claimed |