Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553036 | 1.00 | THRB (0.42) | THRBMAPTAPPF2RL3TP53 | |
| SCHEMBL8555297 | 0.90 | THRB (0.43) | THRBMAPTAPPF2RL3TP53 | |
| SCHEMBL8554248 | 0.86 | MAPT (0.43) | THRBMAPTAPPTP53KDM4E | |
| SCHEMBL8556781 | 0.85 | KDM4E (0.40) | MAPTTP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8556775 | 0.85 | KDM4E (0.40) | MAPTTP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8556548 | 0.80 | THRB (0.53) | THRBMAPTAPPF2RL3TP53 | |
| SCHEMBL8552144 | 0.75 | MAPK1 (0.31) | — | |
| SCHEMBL8552141 | 0.75 | MAPK1 (0.31) | — | |
| SCHEMBL9384918 | 0.72 | RAB9A (0.56) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3668984 | 0.71 | MAPT (0.59) | THRBMAPTF2RL3TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0554957-B1 | Thiazole derivatives of alkoxyacrylates with a fungicidal activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1998-04-15 | — | — | EP | claimed |