Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981781 | 0.81 | SMN1; SMN2 (0.47) | L3MBTL1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL23615217 | 0.78 | L3MBTL1 (0.64) | L3MBTL1POLBALDH1A1MEN1MAPT | |
| SCHEMBL1809197 | 0.77 | L3MBTL1 (0.68) | L3MBTL1POLBALDH1A1MEN1MAPT | |
| SCHEMBL17895483 | 0.77 | L3MBTL1 (0.62) | L3MBTL1POLBALDH1A1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL12080962 | 0.76 | L3MBTL1 (0.66) | L3MBTL1POLBALDH1A1MEN1MAPT | |
| SCHEMBL8556549 | 0.74 | L3MBTL1 (0.59) | L3MBTL1POLBALDH1A1MEN1MAPT | |
| SCHEMBL758061 | 0.74 | L3MBTL1 (1.00) | L3MBTL1POLBMAPTKMT2ANPC1 | |
| SCHEMBL18471674 | 0.73 | L3MBTL1 (0.62) | L3MBTL1POLBALDH1A1MEN1MAPT | |
| SCHEMBL2744060 | 0.73 | L3MBTL1 (0.62) | L3MBTL1POLBALDH1A1MEN1MAPT | |
| SCHEMBL25083597 | 0.73 | L3MBTL1 (0.62) | L3MBTL1POLBALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454511-B1 | N-substituted heterocycle derivatives, their preparation, compositions containing them | SANOFI SA (FR) | 1998-06-17 | — | — | EP | claimed |