Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826401 | 0.82 | PTGS1 (0.41) | PTGS2PTGS1NFE2L2ACHEALOX5 | |
| SCHEMBL867378 | 0.77 | PTGS2 (0.41) | PTGS2PTGS1NFE2L2HTR2AHTR2C | |
| SCHEMBL1350147 | 0.77 | ALDH1A1 (0.48) | PTGS2PTGS1NFE2L2HTR2AHTR2C | |
| SCHEMBL2949202 | 0.76 | AMY1A (0.44) | KDM4EBACE1 | |
| SCHEMBL13678718 | 0.76 | PTGS1 (0.43) | PTGS2PTGS1NFE2L2HTR2AHTR2C | |
| SCHEMBL18906997 | 0.76 | PTGS1 (0.43) | PTGS2PTGS1NFE2L2HTR2AHTR2C | |
| SCHEMBL20125001 | 0.74 | PTGS1 (0.46) | PTGS2PTGS1NFE2L2HTR2AHTR2C | |
| SCHEMBL28757498 | 0.74 | PTGS2 (0.39) | PTGS2PTGS1NFE2L2HTR2AHTR2C | |
| SCHEMBL19677216 | 0.74 | PTGS1 (0.42) | PTGS2PTGS1NFE2L2HTR2AHTR2C | |
| SCHEMBL2097320 | 0.74 | PTGS2 (0.42) | PTGS2PTGS1NFE2L2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816362-A1 | THIAZOLE DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1998-01-07 | — | — | EP | disclosed |