Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL527147 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL10609772 | 0.80 | CA4 (0.40) | CA4 | |
| Hydrochloric Acid SCHEMBL11396330 | 0.78 | CA4 (0.67) | CA4 | |
| Hydrochloric Acid SCHEMBL3896226 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL446648 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL10940122 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL344232 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL28508184 | 0.78 | — | — | |
| Bromide SCHEMBL1537968 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL439803 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5905141-A | Ultra pure hemoglobin solutions and blood substitutes | BIOPURE CORPORATION (US) | 1999-05-18 | — | — | US | disclosed |
| US-5618919-A | CENTRIFUGING WHOLE BLOOD IN BOWL-TYPE CENTRIFUGE, SEPARATING ERYTHROCYTES FROM LEUKOCYTES, DURING CENTRIFUGING ERYTHROCYTES GET DISRUPTED FORMING ENDOTOXIN-FREE HEMOGLOBIN WHICH IS SEMI-SYNTHETIC BLOOD-SUBSTITUTE | BIOPURE CORPORTION (US) | 1997-04-08 | — | — | US | disclosed |
| US-5296465-A | Containing crosslinked hemoglobin in aqueous carrier medium | BIOPURE CORPORATION (US) | 1994-03-22 | — | — | US | disclosed |
| US-5084558-A | Hemoglobin solution formed by fraction of blood, separation and crosslinking | BIOPURE CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |