Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558994 | 0.88 | ADORA3 (0.55) | ADORA3EGFRKDM4EALDH1A1ADORA1 | |
| SCHEMBL8558992 | 0.83 | CHEK1 (0.44) | ADORA3KDM4EALDH1A1 | |
| SCHEMBL8553602 | 0.81 | PDE5A (0.41) | ALDH1A1KMO | |
| SCHEMBL8559477 | 0.80 | CHEK1 (0.51) | — | |
| SCHEMBL8554829 | 0.78 | PDE9A (0.61) | PPARGGPR17KMO | |
| SCHEMBL8557272 | 0.77 | CHEK1 (0.44) | ADORA3KDM4E | |
| SCHEMBL3599601 | 0.76 | ADORA3 (0.43) | ADORA3FFAR1PPARGGPR17KMO | |
| SCHEMBL8558719 | 0.76 | ADORA3 (0.50) | ADORA3EGFRADORA1 | |
| SCHEMBL3600026 | 0.75 | PDE9A (0.43) | ADORA3FFAR1PPARGKDM4EALDH1A1 | |
| SCHEMBL8556228 | 0.74 | ADORA3 (0.50) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | disclosed |