Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | LTK | P29376 | 1/20 | 0.42 |
| ▸ | GRK5 | P34947 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | PRKX | P51817 | 1/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556735 | 0.88 | ADORA3 (0.48) | ADORA3KDM4EALDH1A1EGFRADORA1 | |
| SCHEMBL8555427 | 0.82 | KDM4E (0.42) | ADORA3KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL8558865 | 0.81 | CHEK1 (0.56) | KDM4EALDH1A1LMNAHSD17B10CHEK1 | |
| SCHEMBL8559059 | 0.79 | CHEK1 (0.49) | ADORA3KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL8558719 | 0.73 | ADORA3 (0.50) | ADORA3EGFRADORA1 | |
| SCHEMBL8558992 | 0.72 | CHEK1 (0.44) | ADORA3KDM4EALDH1A1LMNACHEK1 | |
| SCHEMBL8555388 | 0.71 | ADORA3 (0.57) | ADORA3CHEK1DAPK3PRKD3MET | |
| SCHEMBL406481 | 0.71 | ADORA3 (1.00) | ADORA3 | |
| SCHEMBL3579520 | 0.71 | PDE9A (0.59) | ADORA3KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL8554724 | 0.71 | PDE5A (0.48) | KDM4EALDH1A1LMNAHSD17B10EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | disclosed |