Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | PDE9A | O76083 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557983 | 0.88 | DAO (0.43) | ADORA3DAOADORA1 | |
| SCHEMBL8556228 | 0.83 | ADORA3 (0.50) | ADORA3PDE5APDE9A | |
| SCHEMBL8557784 | 0.82 | PDE5A (0.47) | PDE5APDE9A | |
| SCHEMBL8553393 | 0.82 | PDE2A (0.49) | ADORA3PDE5APDE9AADORA1 | |
| SCHEMBL8559120 | 0.78 | ADORA3 (0.50) | ADORA3PDE5APDE9A | |
| SCHEMBL8555388 | 0.77 | ADORA3 (0.57) | ADORA3 | |
| SCHEMBL8556735 | 0.76 | ADORA3 (0.48) | ADORA3EGFRADORA1 | |
| SCHEMBL8558994 | 0.73 | ADORA3 (0.55) | ADORA3EGFRADORA1 | |
| SCHEMBL7351886 | 0.72 | PDE5A (0.50) | ADORA3PDE5APDE9A | |
| SCHEMBL8554724 | 0.69 | PDE5A (0.48) | PDE5APDE9AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | disclosed |