Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.62 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7034776 | 0.82 | MEP1B (0.46) | CA2MEP1BALDH1A1PKMKMT2A | |
| SCHEMBL13461866 | 0.82 | KAT6A (0.42) | CA2KAT6AMEP1BALDH1A1PTGS2 | |
| SCHEMBL8285549 | 0.79 | CA2 (0.64) | CA2ALDH1A1CA1CYP3A4CYP2C9 | |
| SCHEMBL3710861 | 0.79 | CA2 (0.67) | CA2ALDH1A1CA12CA1CA3 | |
| SCHEMBL10058972 | 0.79 | CA2 (0.62) | CA2CA12CA1CA3CA4 | |
| SCHEMBL10531346 | 0.77 | CA2 (1.00) | CA2CA12CA1CA3CA4 | |
| SCHEMBL29385904 | 0.76 | KAT6A (0.40) | CA2KAT6AMEP1BALDH1A1CA1 | |
| SCHEMBL3163671 | 0.76 | KAT6A (0.40) | CA2KAT6AMEP1BALDH1A1CA1 | |
| SCHEMBL4132176 | 0.75 | CNR2 (0.43) | KAT6AMEP1BPTGS2KMT2AMEN1 | |
| SCHEMBL17376428 | 0.75 | KAT6A (0.38) | CA2KAT6AMEP1BPTGS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856002-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1998-08-05 | — | — | EP | disclosed |
| WO-1997009328-A1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | PHARMACIA & UPJOHN COMPANY (US) | 1997-03-13 | — | — | WO | disclosed |