Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407448 | 0.83 | RAPGEF4 (0.46) | MEP1BALDH1A1PKMRAPGEF4HPGD | |
| SCHEMBL8285549 | 0.82 | CA2 (0.64) | CA2ALDH1A1HSD17B10SMN1; SMN2TP53 | |
| SCHEMBL8556738 | 0.82 | CA2 (0.62) | MEP1BCA2ALDH1A1PKMKMT2A | |
| SCHEMBL7036105 | 0.81 | MEP1B (0.43) | MEP1BALDH1A1PKMRAPGEF4HPGD | |
| SCHEMBL4394138 | 0.81 | MEP1B (0.43) | MEP1BALDH1A1PKMRAPGEF4HPGD | |
| SCHEMBL10407436 | 0.80 | RAPGEF4 (0.50) | MEP1BALDH1A1PKMRAPGEF4HPGD | |
| SCHEMBL3253706 | 0.80 | MEP1B (0.47) | MEP1BALDH1A1PKMRAPGEF4HPGD | |
| SCHEMBL10407445 | 0.80 | RAPGEF4 (0.44) | MEP1BALDH1A1PKMRAPGEF4HPGD | |
| SCHEMBL4390836 | 0.79 | ALDH1A1 (0.43) | MEP1BALDH1A1PKMRAPGEF4HPGD | |
| SCHEMBL8936961 | 0.77 | CA2 (0.40) | MEP1BCA2ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841323-B1 | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL CO (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6201131-B1 | REACTING A 2-(ARYLSUFONYL) ETHANOL DERIVATIVE WITH AN ACID ANHYDRIDE IN PRESENCE OF A BASE, FURTHER REACTING THIS WITH AN AROMATIC HALIDE IN THE PRESENCE OF A PALLADIUM CATALYST; USEFUL AS INTERMEDIATES TO DRUGS, AGROCHEMICALS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-03-13 | — | — | US | disclosed |
| US-5902905-A | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-05-11 | — | — | US | disclosed |
| EP-0841323-A2 | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-05-13 | — | — | EP | disclosed |