Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | PDE9A | O76083 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475619 | 0.82 | HDAC6 (0.43) | HDAC6ALDH1A1PDE9AP4HTMMEN1 | |
| SCHEMBL29063426 | 0.78 | HDAC6 (0.39) | HDAC6ALDH1A1ALOX15NPSR1KDM4E | |
| SCHEMBL30464690 | 0.75 | ALDH1A1 (0.33) | HDAC6ALDH1A1ALOX15KDM4EHSD17B10 | |
| SCHEMBL14038235 | 0.72 | ALOX15 (0.55) | ALDH1A1ALOX15LMNANPSR1KDM4E | |
| SCHEMBL9645804 | 0.70 | ALDH1A1 (0.51) | HDAC6ALDH1A1ALOX15LMNANPSR1 | |
| SCHEMBL6598308 | 0.68 | ALOX15 (0.55) | ALDH1A1ALOX15LMNANPSR1TSHR | |
| SCHEMBL13900377 | 0.67 | ALDH1A1 (0.41) | ALDH1A1ALOX15LMNANPSR1KDM4E | |
| SCHEMBL14037790 | 0.67 | CYP2C19 (0.38) | ALDH1A1ALOX15LMNANPSR1KDM4E | |
| SCHEMBL1768417 | 0.67 | CYP11B1 (0.41) | HDAC6ALDH1A1NPSR1KDM4E | |
| SCHEMBL22437429 | 0.67 | NR1H4 (0.48) | HDAC6ALDH1A1ALOX15LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| US-5552420-A | TREATING PICORNAVIRAL INFECTIONS | STERLING WINTHROP INC. (US) | 1996-09-03 | — | — | US | disclosed |