Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CFD | P00746 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | PLK1 | P53350 | 4/20 | 0.55 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922018 | 0.89 | L3MBTL1 (0.69) | L3MBTL1CYP2C9HPGDEPHX1ALDH1A1 | |
| SCHEMBL6442708 | 0.86 | EPHX1 (0.73) | L3MBTL1EPHX1ALDH1A1HTTPOLB | |
| SCHEMBL9119762 | 0.86 | EPHX1 (0.58) | L3MBTL1CYP2C9HPGDEPHX1ALDH1A1 | |
| SCHEMBL29098671 | 0.85 | GAA (0.70) | L3MBTL1EPHX1ALDH1A1HTTPOLB | |
| SCHEMBL10362736 | 0.85 | GAA (0.70) | L3MBTL1EPHX1ALDH1A1HTTPOLB | |
| SCHEMBL10363617 | 0.85 | GAA (0.70) | L3MBTL1EPHX1ALDH1A1HTTPOLB | |
| SCHEMBL13614088 | 0.83 | GAA (0.71) | L3MBTL1CYP2C9HPGDALDH1A1POLB | |
| SCHEMBL11110593 | 0.82 | POLB (0.81) | L3MBTL1CYP2C9HPGDEPHX1ALDH1A1 | |
| SCHEMBL415266 | 0.82 | L3MBTL1 (0.60) | L3MBTL1CYP2C9HPGDEPHX1ALDH1A1 | |
| SCHEMBL466141 | 0.81 | PLK1 (0.63) | L3MBTL1CYP2C9HPGDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653423-B1 | Process for the preparation of substituted quinazoline-2,4-diones | CLARIANT GMBH (DE) | 1999-06-16 | — | — | EP | claimed |
| EP-0653423-A1 | Process for the preparation of substituted quinazoline-2,4-diones | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | disclosed |