Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | CFD | P00746 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MASP2 | O00187 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922018 | 0.87 | L3MBTL1 (0.69) | GAACFDKMT2AKDM4EABCC1 | |
| SCHEMBL3352186 | 0.85 | GAA (0.69) | GAAKMT2AKDM4EPOLBMEN1 | |
| SCHEMBL10363515 | 0.83 | GAA (1.00) | GAAKMT2AKDM4EPOLBHPGD | |
| SCHEMBL8687136 | 0.83 | KMT2A (0.54) | GAACFDKMT2AKDM4EABCC1 | |
| SCHEMBL4749159 | 0.83 | DHODH (0.69) | CFDKMT2AKDM4EMEN1MAPT | |
| SCHEMBL8556765 | 0.83 | L3MBTL1 (0.68) | CFDKMT2APOLBCYP2C9HPGD | |
| SCHEMBL19892654 | 0.82 | GAA (0.66) | GAACFDKMT2AKDM4EPOLB | |
| SCHEMBL8686791 | 0.80 | ALDH1A1 (0.70) | CFDKMT2AKDM4EABCC1POLB | |
| SCHEMBL8458301 | 0.80 | CFD (0.65) | GAACFDKMT2AKDM4ECYP2C9 | |
| SCHEMBL14398081 | 0.80 | CFD (0.65) | GAACFDKMT2AKDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432700-B1 | SPIRO-HYDANTOIN COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2009-11-04 | — | — | EP | disclosed |