Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002809 | 0.88 | ALDH1A1 (0.37) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL8014934 | 0.83 | — | — | |
| SCHEMBL29013573 | 0.78 | KMT2A (0.46) | KMT2AALDH1A1MEN1MAPTL3MBTL1 | |
| SCHEMBL222564 | 0.77 | KMT2A (0.39) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL922271 | 0.75 | L3MBTL1 (0.40) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL7259415 | 0.75 | KMT2A (0.38) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL922200 | 0.75 | KMT2A (0.38) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL10942351 | 0.75 | TSHR (0.47) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL16146074 | 0.75 | ALDH1A1 (0.38) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL650776 | 0.75 | MIF (0.36) | KMT2AALDH1A1MEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |
| WO-1994008904-A1 | ANTIFOULING COATING COMPOSITION AND METHOD | DUKE UNIVERSITY (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5259701-A | Antifouling coating composition comprising furan compounds, method for protecting aquatic structures, and articles protected against fouling organisms | ROHM AND HAAS COMPANY (US) | 1993-11-09 | — | — | US | disclosed |