SCHEMBL650776

SCHEMBL650776

[CH2]C(CC(CC)c1ccco1)c1ccco1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.36
ALDH1A1 P00352 7/20 0.35
KMT2A Q03164 6/20 0.35
MEN1 O00255 5/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HPGD P15428 2/20 0.33
GLA P06280 1/20 0.33
RECQL P46063 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
POLB P06746 2/20 0.32
PKM P14618 1/20 0.32
PTPN1 P18031 1/20 0.32
PTPN7 P35236 1/20 0.32
BLM P54132 1/20 0.32
ESR2 Q92731 1/20 0.32
TP53 P04637 1/20 0.31
ALOX5 P09917 1/20 0.31
CYP2C19 P33261 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8014934 0.82
SCHEMBL12464824 0.82 MIF (0.43) MIFALDH1A1KMT2AMEN1MAPT
SCHEMBL7163947 0.80 MIF (0.40) MIFALDH1A1KMT2AMEN1MAPT
SCHEMBL11464100 0.77 MIF (0.38) MIFALDH1A1KMT2AMEN1MAPT
SCHEMBL1269466 0.77 MIF (0.38) MIFALDH1A1KMT2AMEN1MAPT
SCHEMBL827034 0.75 MIF (0.39) MIFALDH1A1KMT2AMEN1MAPT
SCHEMBL11354508 0.75 MIF (0.42) MIFALDH1A1KMT2AMEN1MAPT
SCHEMBL8556811 0.75 KMT2A (0.38) ALDH1A1KMT2AMEN1MAPTKDM4E
SCHEMBL14785579 0.72 ALDH1A1 (0.40) MIFALDH1A1KMT2AMEN1MAPT
SCHEMBL6002809 0.72 ALDH1A1 (0.37) ALDH1A1KMT2AMEN1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103122086-A Filled rubber compounds with improved processability CIBA SC HOLDING AG 2013-05-29 CN disclosed
US-8252862-B2 Silane coupling agents for filled rubbers BASF SE (DE) 2012-08-28 US disclosed
CN-102482851-A Papermaking using high solids glyoxylated-polyacrylamide and silicon-containing microparticles and articles made therefrom BUCKMAN LABOR INC 2012-05-30 CN disclosed
CN-102482851-A Papermaking using high solids glyoxylated-polyacrylamide and silicon-containing microparticles and articles made therefrom BUCKMAN LABOR INC 2012-05-30 CN disclosed
US-8118976-B2 Process for the production of a cellulosic product AKZO NOBEL N.V. (NL) 2012-02-21 US disclosed
US-8119710-B2 Filled rubber compounds with improved processability BASF SE (DE) 2012-02-21 US disclosed
EP-2190912-B1 SILANE COUPLING AGENTS FOR FILLED RUBBERS BASF SE (DE) 2011-11-23 EP disclosed
US-20100317778-A1 Filled Rubber Compounds with Improved Processability CIBA CORPORATION 2010-12-16 US disclosed
US-20100261826-A1 SILANE COUPLING AGENTS FOR FILLED RUBBERS BASF SE (DE) 2010-10-14 US disclosed
US-20100236737-A1 PROCESS FOR THE PRODUCTION OF A CELLULOSIC PRODUCT AKZO NOBEL N.V. (NL) 2010-09-23 US disclosed
WO-2009034016-A1 SILANE COUPLING AGENTS FOR FILLED RUBBERS BASF SE (CH) 2009-03-19 WO disclosed
WO-2008143580-A1 PROCESS FOR THE PRODUCTION OF A CELLULOSIC PRODUCT AKZO NOBEL N.V. (NL) 2008-11-27 WO disclosed
CN-100436523-C Coupling agents between filler and elastomer EP20030104689 (CH) 2008-11-26 CN disclosed
US-20080287578-A1 Coupling Agents Between Filler and Elastomer CIBA SPECIALTY CHEMICALS CORP. 2008-11-20 US disclosed
CN-101268088-A Filled rubber compound with improved processability CIBA HOLDING INC (CH) 2008-09-17 CN disclosed
EP-1928888-A1 FILLED RUBBER COMPOUNDS WITH IMPROVED PROCESSABILITY Ciba Holding Inc. (CH) 2008-06-11 EP disclosed
WO-2007039416-A1 FILLED RUBBER COMPOUNDS WITH IMPROVED PROCESSABILITY CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-04-12 WO disclosed
CN-1894327-A Coupling agents between fillers and elastomers EP20030104689 (CH) 2007-01-10 CN disclosed
EP-1727858-A1 COUPLING AGENTS BETWEEN FILLER AND ELASTOMER Ciba Specialty Chemicals Holding Inc. (CH) 2006-12-06 EP disclosed
WO-2005059022-A1 COUPLING AGENTS BETWEEN FILLER AND ELASTOMER CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317778-A1 Filled Rubber Compounds with Improved Processability RER1, RIF1, REV1 MIF 4533/4885ALDH1A1 1605/4885KMT2A 2949/4885
US-20100261826-A1 SILANE COUPLING AGENTS FOR FILLED RUBBERS RER1, REV1, RIOX2 MIF 3906/4885ALDH1A1 1256/4885KMT2A 1874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.