Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.56 |
| ▸ | PPARD | Q03181 | 4/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556876 | 1.00 | ALOX5 (0.56) | ALOX5PPARDPPARAMAPTL3MBTL1 | |
| SCHEMBL8557228 | 0.90 | ALOX5 (0.46) | ALOX5PPARDPPARAMAPTL3MBTL1 | |
| SCHEMBL8555939 | 0.83 | KCNH2 (0.43) | ALOX5HDAC6 | |
| SCHEMBL8555948 | 0.83 | KCNH2 (0.43) | ALOX5HDAC6 | |
| SCHEMBL8557153 | 0.80 | MEN1 (0.37) | ALOX5PPARDPPARAMAPTL3MBTL1 | |
| SCHEMBL8626737 | 0.80 | NPC1 (0.60) | ALOX5MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL8626714 | 0.80 | NPC1 (0.60) | ALOX5MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL8622668 | 0.79 | NPC1 (0.58) | ALOX5MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL8622647 | 0.79 | NPC1 (0.58) | ALOX5MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL8556881 | 0.78 | ALOX5 (0.72) | ALOX5PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |