Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555939 | 0.83 | KCNH2 (0.43) | ALOX5 | |
| SCHEMBL8555948 | 0.83 | KCNH2 (0.43) | ALOX5 | |
| SCHEMBL8556876 | 0.80 | ALOX5 (0.56) | MEN1KMT2AMAPTKDM4EL3MBTL1 | |
| SCHEMBL8556884 | 0.80 | ALOX5 (0.56) | MEN1KMT2AMAPTKDM4EL3MBTL1 | |
| SCHEMBL8554711 | 0.77 | PARP10 (0.53) | MAPTKDM4EALOX5LMNAHPGD | |
| SCHEMBL8554727 | 0.77 | PARP10 (0.53) | MAPTKDM4EALOX5LMNAHPGD | |
| SCHEMBL8557151 | 0.77 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL8557021 | 0.76 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL8626714 | 0.76 | NPC1 (0.60) | MEN1KMT2AMAPTKDM4EL3MBTL1 | |
| SCHEMBL8626737 | 0.76 | NPC1 (0.60) | MEN1KMT2AMAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |