Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 14/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555939 | 1.00 | KCNH2 (0.43) | KCNH2MRGPRX4ALOX5GPBAR1HDAC6 | |
| SCHEMBL8559850 | 0.89 | MEN1 (0.42) | KCNH2MRGPRX4ALOX5HDAC6 | |
| SCHEMBL8557153 | 0.83 | MEN1 (0.37) | ALOX5 | |
| SCHEMBL8556876 | 0.83 | ALOX5 (0.56) | ALOX5HDAC6 | |
| SCHEMBL8556884 | 0.83 | ALOX5 (0.56) | ALOX5HDAC6 | |
| SCHEMBL8554727 | 0.82 | PARP10 (0.53) | ALOX5 | |
| SCHEMBL8554711 | 0.82 | PARP10 (0.53) | ALOX5 | |
| SCHEMBL8559093 | 0.81 | ACACB (0.41) | ALOX5HDAC6 | |
| SCHEMBL8555246 | 0.81 | GPBAR1 (0.61) | ALOX5GPBAR1HDAC6 | |
| SCHEMBL8559073 | 0.81 | ACACB (0.41) | ALOX5HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |