Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555574 | 0.90 | PTGS2 (0.60) | PTGS2PTGS1SMN1; SMN2CYP1A2POLB | |
| SCHEMBL6308685 | 0.78 | PTGS2 (0.60) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL7500813 | 0.76 | PTGS2 (1.00) | PTGS2PTGS1MAOAMAOBKMT2A | |
| SCHEMBL7505580 | 0.76 | PTGS2 (1.00) | PTGS2PTGS1MAOAMAOBKMT2A | |
| SCHEMBL7503991 | 0.76 | PTGS2 (0.67) | PTGS2PTGS1CA2NR4A2MAOA | |
| SCHEMBL7508637 | 0.76 | PTGS2 (0.67) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL7503465 | 0.75 | PTGS2 (0.62) | PTGS2PTGS1CYP3A4HPGDCYP2C19 | |
| SCHEMBL6860698 | 0.75 | PTGS2 (0.59) | PTGS2PTGS1SMN1; SMN2CA1CA2 | |
| SCHEMBL7506875 | 0.74 | PTGS2 (0.61) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL7505886 | 0.74 | PTGS2 (0.58) | PTGS2PTGS1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |