Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | CA12 | O43570 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310934 | 0.89 | RXRA (0.49) | PTGS2PTGS1MAOAMAOBNR4A1 | |
| SCHEMBL6308845 | 0.89 | RXRA (0.49) | PTGS2PTGS1MAOAMAOBNR4A1 | |
| SCHEMBL7503465 | 0.88 | PTGS2 (0.62) | PTGS2PTGS1MAOAMAOBNR4A1 | |
| SCHEMBL6314953 | 0.86 | CA9 (0.49) | PTGS2PTGS1CA1CA2CA12 | |
| SCHEMBL8607283 | 0.86 | PTGS2 (0.57) | PTGS2PTGS1MAOAMAOBNR4A2 | |
| SCHEMBL6309705 | 0.85 | PTGS1 (0.46) | PTGS2PTGS1MAOAMAOBNR4A1 | |
| SCHEMBL7508637 | 0.84 | PTGS2 (0.67) | PTGS2PTGS1MAOAMAOBCA1 | |
| SCHEMBL6310443 | 0.84 | PTGS2 (0.60) | PTGS2PTGS1MAOAMAOBNR4A1 | |
| SCHEMBL6860698 | 0.83 | PTGS2 (0.59) | PTGS2PTGS1MAOAMAOBNR4A2 | |
| SCHEMBL6314997 | 0.83 | PTGS2 (0.52) | PTGS2PTGS1MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875785-B2 | Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors | PHARMACIA CORPORATION (US) | 2005-04-05 | — | — | US | claimed |