Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564269 | 0.83 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL9236961 | 0.82 | AVPR2 (0.66) | AVPR2AVPR1A | |
| SCHEMBL8563344 | 0.82 | AVPR2 (0.81) | AVPR2AVPR1A | |
| SCHEMBL8560873 | 0.81 | ACHE (0.60) | AVPR2AVPR1A | |
| SCHEMBL8558993 | 0.81 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL8556852 | 0.81 | AVPR1A (0.59) | AVPR2AVPR1A | |
| SCHEMBL8560800 | 0.81 | AVPR2 (0.79) | AVPR2AVPR1A | |
| SCHEMBL8562029 | 0.80 | AVPR2 (0.58) | AVPR2AVPR1A | |
| SCHEMBL8559764 | 0.80 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL8558555 | 0.80 | AVPR2 (0.55) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |