Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | EGFR | P00533 | 5/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266460 | 0.87 | GAA (0.67) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL1368071 | 0.81 | GAA (1.00) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL8563763 | 0.81 | NPSR1 (0.67) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL8560344 | 0.81 | GAA (0.67) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL11538460 | 0.78 | GAA (0.42) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL5783916 | 0.74 | MAOA (0.65) | GAANPSR1EGFRMAOAMAOB | |
| SCHEMBL766354 | 0.74 | ALOX5 (0.65) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL7345533 | 0.72 | MAPT (0.56) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL6970933 | 0.71 | NPSR1 (0.67) | GAANPSR1MEN1MAPTKMT2A | |
| SCHEMBL9266525 | 0.71 | GAA (0.67) | GAANPSR1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |