Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA4 | P22748 | 4/20 | 0.41 |
| ▸ | CA6 | P23280 | 4/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA5A | P35218 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557126 | 0.96 | PLCG1 (0.47) | PLCG1RECQLCA1CA2CA4 | |
| SCHEMBL8559623 | 0.80 | HDAC1 (0.50) | CA1CA2ALOX15CA12CA9 | |
| SCHEMBL8558350 | 0.76 | ATM (0.42) | CA1CA2ALOX15CA12CA9 | |
| SCHEMBL2451404 | 0.74 | PLCG1 (0.60) | PLCG1RECQLCA1CA2CA4 | |
| SCHEMBL7394460 | 0.74 | MMP9 (0.37) | PLCG1RECQLCA1CA2CA4 | |
| SCHEMBL8557842 | 0.71 | KMT2A (0.43) | CA1CA2ALOX15CA5ACA9 | |
| SCHEMBL8559958 | 0.71 | ATM (0.43) | CA1CA2ALOX15CA12CA9 | |
| SCHEMBL15915533 | 0.71 | PLCG1 (0.61) | PLCG1RECQLCA1CA2CA4 | |
| SCHEMBL28023659 | 0.71 | PLCG1 (0.60) | PLCG1RECQLCA1CA2CA4 | |
| SCHEMBL7076389 | 0.70 | ALOX15 (0.53) | CA2EPHX2ALOX15MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |