Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10310340 | 0.89 | L3MBTL1 (0.61) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL8558350 | 0.83 | ATM (0.42) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL8557517 | 0.80 | PLCG1 (0.46) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL8557842 | 0.79 | KMT2A (0.43) | ALOX15CA2KDM4EALDH1A1LMNA | |
| SCHEMBL8559958 | 0.79 | ATM (0.43) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL576918 | 0.77 | KEAP1 (0.63) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL14952114 | 0.76 | EPHX2 (0.58) | HDAC1HDAC3SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8558274 | 0.76 | GAA (0.43) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL10626503 | 0.75 | HDAC1 (0.65) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL21171920 | 0.75 | TRPV1 (0.56) | L3MBTL1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |