Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074317 | 0.72 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL8129014 | 0.72 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL8879834 | 0.69 | ADRB2 (0.44) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6074550 | 0.69 | ADRB2 (0.39) | ADRB2ADRB1ADRB3 | |
| SCHEMBL2429368 | 0.67 | — | — | |
| SCHEMBL10341872 | 0.67 | ADRB2 (0.45) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3439382 | 0.65 | ADRB2 (0.33) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3466377 | 0.65 | ADRB2 (0.33) | ADRB2ADRB1ADRB3 | |
| SCHEMBL4538650 | 0.63 | ADRB2 (0.54) | ADRB2ADRB1ADRB3 | |
| SCHEMBL10520059 | 0.63 | CHRNA4 (0.38) | ADRB2ADRB1ADRB3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853619-A1 | DISUBSTITUTED PIPERIDINE DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997013769-A1 | DISUBSTITUTED PIPERIDINE DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-04-17 | — | — | WO | disclosed |