Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341872 | 0.85 | ADRB2 (0.45) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6074550 | 0.84 | ADRB2 (0.39) | ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL8129014 | 0.83 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6074317 | 0.83 | ADRB2 (0.40) | ADRB2ADRB1ADRB3 | |
| SCHEMBL5789095 | 0.78 | ALDH1A1 (0.40) | LMNA | |
| SCHEMBL21009819 | 0.78 | ALDH1A1 (0.40) | LMNA | |
| SCHEMBL4538650 | 0.77 | ADRB2 (0.54) | ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL3439382 | 0.76 | ADRB2 (0.33) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3466377 | 0.76 | ADRB2 (0.33) | ADRB2ADRB1ADRB3 | |
| SCHEMBL5791247 | 0.76 | LMNA (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602160-A | MUSCLE RELAXANT | MITSUI TOATSU CHEMICALS INCORPORATED (JP) | 1997-02-11 | — | — | US | disclosed |
| US-5498619-A | MUSCLE RELAXANTS, POLLAKIUREA CURING AGENTS AND MUSCLE SPASMS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0414391-B1 | Aminoketone derivatives and use thereof | MITSUI TOATSU CHEMICALS (JP) | 1995-03-15 | — | — | EP | disclosed |
| US-5338857-A | Muscle relaxant | MITSUI TOATSU CHEMICALS INCORPORATED (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0414391-A2 | Aminoketone derivatives and use thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-02-27 | — | — | EP | disclosed |
| EP-0207955-B1 | PROCESS FOR THE PREPARATION OF 3,5-DISUBSTITUTED ISOXAZOLES | ZAMBON S.p.A. (IT) | 1990-02-07 | — | — | EP | disclosed |
| US-4772719-A | FROM DIHALOFORMALDOXIME AND ALKYNE, CYCLIZATION | ZAMBON S.P.A. (IT) | 1988-09-20 | — | — | US | disclosed |
| EP-0207955-A1 | PROCESS FOR THE PREPARATION OF 3,5-DISUBSTITUTED ISOXAZOLES. | ZAMBON SPA (IT) | 1987-01-14 | — | — | EP | disclosed |
| WO-1986003490-A1 | PROCESS FOR THE PREPARATION OF 3,5-DISUBSTITUTED ISOXAZOLES | ZAMBON S.P.A. (IT) | 1986-06-19 | — | — | WO | disclosed |