Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.86 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556404 | 0.89 | MEN1 (0.69) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15095866 | 0.84 | MEN1 (0.73) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL8559148 | 0.84 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL29227073 | 0.82 | TUBB4A (0.78) | MEN1KMT2A | |
| SCHEMBL23318259 | 0.82 | MEN1 (0.65) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8556958 | 0.82 | MEN1 (0.58) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8558637 | 0.81 | LMNA (0.58) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL8558009 | 0.81 | CA1 (0.69) | MEN1KMT2APOLBLMNA | |
| SCHEMBL8559166 | 0.80 | LMNA (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1915903 | 0.80 | MEN1 (0.70) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617022-B1 | 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound | BANYU PHARMA CO LTD (JP) | 1998-02-11 | — | — | EP | disclosed |