SCHEMBL23318259

SCHEMBL23318259

COc1cc(CCC(=O)NCCc2ccc(O)cc2)cc(O)c1O

nearest known ligand 0.65

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
ALDH1A1 P00352 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2376785 0.89 MEN1 (0.67) MEN1KMT2AALDH1A1
SCHEMBL1915903 0.83 MEN1 (0.70) MEN1KMT2A
SCHEMBL2378930 0.82 MEN1 (0.65) MEN1KMT2A
SCHEMBL8557569 0.82 MEN1 (0.86) MEN1KMT2AALDH1A1
SCHEMBL19060661 0.81 MTNR1A (0.69) MEN1KMT2A
SCHEMBL29079535 0.81 AKR1B1 (0.70) MEN1KMT2A
SCHEMBL2379821 0.81 KDM4E (0.65)
SCHEMBL14432087 0.80 KMT2A (0.66) MEN1KMT2AALDH1A1
SCHEMBL2378518 0.80 TRPV1 (0.68) MEN1KMT2AALDH1A1
SCHEMBL4022887 0.80 KMT2A (0.87) MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230270699-A1 METHOD FOR MODULATING METABOLISM Sanford Burnham Prebys Medical Discovery Institute 2023-08-31 US disclosed
US-11382880-B2 Method for improving digestive health BRIGHTSEED, INC. (US) 2022-07-12 US disclosed
US-20210128499-A1 METHOD FOR IMPROVING DIGESTIVE HEALTH BRIGHTSEED, INC. 2021-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270699-A1 METHOD FOR MODULATING METABOLISM GOT2, GYS2, PC MEN1 3891/4885KMT2A 2636/4885ALDH1A1 603/4885
US-11382880-B2 Method for improving digestive health FABP6, FABP2, PNLIP MEN1 2367/4885KMT2A 3396/4885ALDH1A1 723/4885
US-20210128499-A1 METHOD FOR IMPROVING DIGESTIVE HEALTH FABP6, FABP2, PNLIP MEN1 2367/4885KMT2A 3396/4885ALDH1A1 723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.