Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557174 | 0.89 | KEAP1 (0.52) | KEAP1SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL8558962 | 0.87 | KEAP1 (0.50) | KEAP1SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL8557810 | 0.85 | KEAP1 (0.48) | KEAP1SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL8557309 | 0.85 | KEAP1 (0.48) | KEAP1SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL8555711 | 0.85 | KEAP1 (0.48) | KEAP1SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL8557644 | 0.85 | KEAP1 (0.48) | KEAP1SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL8554312 | 0.79 | USP2 (0.50) | KEAP1SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL4796080 | 0.79 | KEAP1 (0.52) | KEAP1SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL27925537 | 0.78 | USP2 (0.45) | KEAP1SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL27586193 | 0.75 | USP2 (0.50) | KEAP1SMN1; SMN2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |