Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557571 | 0.79 | KEAP1 (0.45) | USP2ANPEPALDH1A1SMN1; SMN2KEAP1 | |
| SCHEMBL372508 | 0.77 | USP2 (0.58) | USP2ANPEPALDH1A1SMN1; SMN2KEAP1 | |
| SCHEMBL4201455 | 0.77 | USP2 (0.58) | USP2ANPEPALDH1A1SMN1; SMN2KEAP1 | |
| SCHEMBL8557174 | 0.76 | KEAP1 (0.52) | ANPEPALDH1A1SMN1; SMN2KEAP1KDM4E | |
| Hydrochloric Acid SCHEMBL18726103 | 0.75 | ALDH1A1 (0.50) | USP2ANPEPALDH1A1SMN1; SMN2KEAP1 | |
| SCHEMBL8558962 | 0.75 | KEAP1 (0.50) | ALDH1A1SMN1; SMN2KEAP1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL31053687 | 0.75 | USP2 (0.56) | USP2ANPEPALDH1A1SMN1; SMN2KEAP1 | |
| SCHEMBL8557644 | 0.74 | KEAP1 (0.48) | ALDH1A1SMN1; SMN2KEAP1KDM4ELMNA | |
| SCHEMBL8557309 | 0.74 | KEAP1 (0.48) | ALDH1A1SMN1; SMN2KEAP1KDM4ELMNA | |
| SCHEMBL8555711 | 0.74 | KEAP1 (0.48) | ALDH1A1SMN1; SMN2KEAP1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |