Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 5/20 | 0.44 |
| ▸ | WEE1 | P30291 | 5/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.39 |
| ▸ | CDK4 | P11802 | 3/20 | 0.39 |
| ▸ | CCND1 | P24385 | 3/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 3/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 3/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.39 |
| ▸ | PRKACA | P17612 | 2/20 | 0.39 |
| ▸ | PRKACG | P22612 | 2/20 | 0.39 |
| ▸ | PRKACB | P22694 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559979 | 0.99 | CHEK1 (0.43) | CHEK1WEE1CDK1SIGMAR1TRPM2 | |
| SCHEMBL8557009 | 0.94 | CHEK1 (0.47) | CHEK1WEE1CDK1SIGMAR1TRPM2 | |
| SCHEMBL8554507 | 0.93 | SIGMAR1 (0.47) | CHEK1WEE1CDK1SIGMAR1TRPM2 | |
| SCHEMBL3174237 | 0.92 | CHEK1 (0.47) | CHEK1WEE1CDK1SIGMAR1TRPM2 | |
| SCHEMBL133934 | 0.86 | GSK3B (0.38) | PARP1 | |
| SCHEMBL9152783 | 0.86 | GSK3B (0.38) | PARP1 | |
| SCHEMBL8938070 | 0.86 | GSK3B (0.38) | PARP1 | |
| SCHEMBL4026807 | 0.86 | GSK3B (0.38) | PARP1 | |
| SCHEMBL9151570 | 0.86 | GSK3B (0.38) | PARP1 | |
| SCHEMBL4909203 | 0.86 | GSK3B (0.38) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |