Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561279 | 0.86 | KIF11 (0.37) | MEN1HDAC9HCAR2KIF11EDNRB | |
| SCHEMBL8560374 | 0.84 | MEN1 (0.35) | MEN1HDAC9HCAR2KIF11EDNRB | |
| SCHEMBL8560551 | 0.82 | MEN1 (0.37) | MEN1HDAC9KIF11 | |
| SCHEMBL8555341 | 0.75 | ALDH1A1 (0.39) | MEN1HDAC9HCAR2KIF11EDNRB | |
| SCHEMBL27852609 | 0.69 | ALDH1A1 (0.41) | MEN1HDAC9HCAR2TSHRNPSR1 | |
| SCHEMBL28312964 | 0.68 | TDP1 (0.40) | MEN1HDAC9HCAR2TSHRNPSR1 | |
| SCHEMBL28008400 | 0.67 | HDAC9 (0.41) | MEN1HDAC9HCAR2KIF11TSHR | |
| SCHEMBL27969858 | 0.67 | MEN1 (0.40) | MEN1HDAC9HCAR2TSHRNPSR1 | |
| SCHEMBL7201343 | 0.67 | ALDH1A1 (0.39) | MEN1HDAC9HCAR2KIF11TSHR | |
| SCHEMBL9845298 | 0.67 | ALDH1A1 (0.60) | MEN1HDAC9HCAR2EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538248-B1 | TETRAHYDROISOQUINOLINYLCARBAMATES OF 1,2,3,3A,8,8A-HEXAHYDRO-1,3A,8-TRIMETHYLPYRROLO [2,3-B]INDOLE | HOECHST MARION ROUSSEL INC (US) | 1998-02-11 | — | — | EP | claimed |