SCHEMBL855770

SCHEMBL855770

CC1(C)OC(c2cccs2)CN1C(=O)C(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 1/20 0.34
BRD4 O60885 2/20 0.34
DPP4 P27487 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
ALDH1A1 P00352 5/20 0.33
KDM4E B2RXH2 3/20 0.33
MAPT P10636 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GAA P10253 2/20 0.32
GLA P06280 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32
ADORA2B P29275 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
BRDT Q58F21 1/20 0.32
LMNA P02545 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27283907 1.00 TBXAS1 (0.34) TBXAS1BRD4DPP4SMN1; SMN2ALDH1A1
SCHEMBL9669984 0.85 DPP4 (0.33) TBXAS1BRD4DPP4SMN1; SMN2ALDH1A1
SCHEMBL9667898 0.85 DPP4 (0.33) TBXAS1BRD4DPP4SMN1; SMN2ALDH1A1
SCHEMBL9667891 0.85 DPP4 (0.33) TBXAS1BRD4DPP4SMN1; SMN2ALDH1A1
SCHEMBL856664 0.79 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1KDM4EGAAHPGD
SCHEMBL11019917 0.76 MAPK1 (0.40) ALDH1A1KDM4EHPGD
Furilazole SCHEMBL167569 0.76 ALDH1A1 (0.38) ALDH1A1KDM4EMAPTL3MBTL1HTT
Furilazole SCHEMBL12490154 0.76 ALDH1A1 (0.38) ALDH1A1KDM4EMAPTL3MBTL1HTT
Furilazole SCHEMBL124162 0.76 ALDH1A1 (0.38) ALDH1A1KDM4EMAPTL3MBTL1HTT
Furilazole SCHEMBL8462067 0.76 ALDH1A1 (0.38) ALDH1A1KDM4EMAPTL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902118-B2 Herbicide and repellent adjuvant; reducing foliage retention; preventing damage to crops BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2011-03-08 US claimed
US-6936569-B2 Compositions and methods for protecting cultivated plants from herbicidal injury BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2005-08-30 US claimed
US-20050032645-A1 Compositions and methods for protecting cultivated plants from herbicidal injury BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2005-02-10 US claimed
EP-1258193-A1 Herbicidal compositions of tetrazolinone herbicides and antidotes therefor Syngenta Limited (GB) 2002-11-20 EP claimed
US-20020010096-A1 Compositions and methods for protecting cultivated plants from herbicidal injury BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY 2002-01-24 US claimed
US-6248693-B1 ANTIDOTES FOR HERBICIDES FOR PLANT SAFTENING AGENTS ZENECA LIMITED (GB) 2001-06-19 US claimed
US-6235682-B1 AQUEOUS SOLUTION CONTAINING REPELLENT ADJUVANT BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY 2001-05-22 US claimed
EP-0999748-A1 HERBICIDAL COMPOSITIONS OF TETRAZOLINONE HERBICIDES AND ANTIDOTES THEREFOR ZENECA LIMITED (GB) 2000-05-17 EP claimed
EP-0802732-B1 HERBICIDAL COMPOSITIONS OF 4-BENZOYLISOXAZOLE OR 2-CYANO-1,3-DIONE HERBICIDES AND ANTIDOTES THEREFOR ZENECA LTD (GB) 2000-04-19 EP claimed
EP-0565593-B1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO CO (US) 1999-03-03 EP claimed
WO-1999003348-A1 HERBICIDAL COMPOSITIONS OF TETRAZOLINONE HERBICIDES AND ANTIDOTES THEREFOR ZENECA LIMITED (GB) 1999-01-28 WO claimed
EP-0802732-A1 HERBICIDAL COMPOSITIONS OF 4-BENZOYLISOXAZOLE OR 2-CYANO-1,3-DIONE HERBICIDES AND ANTIDOTES THEREFOR ZENECA LIMITED (GB) 1997-10-29 EP claimed
US-5627131-A Herbicidal compositions of 4-benzoylisoxazole and antidotes therefor ZENECA LIMITED (GB) 1997-05-06 US claimed
WO-1996021357-A1 HERBICIDAL COMPOSITIONS OF 4-BENZOYLISOXAZOLE OR 2-CYANO-1,3-DIONE HERBICIDES AND ANTIDOTES THEREFOR ZENECA LIMITED (GB) 1996-07-18 WO claimed
CN-1081815-A Safe with pyrazolyl sulfonylureas of activity of weeding MONSANTO CO (US) 1994-02-16 CN claimed
EP-0304409-B1 5-HETEROCYCLIC-SUBSTITUTED OXAZOLIDINE HALOACETAMIDES MONSANTO CO (US) 1992-10-28 EP claimed
CN-1063015-A Safe herbicidal sulfonamide compositions MONSANTO CO (US) 1992-07-29 CN claimed
CN-1061322-A The safe of benzoic acid derivative class weed killer herbicide MONSANTO CO (US) 1992-05-27 CN claimed
CN-1052769-A The protective mixture of sulfonylurea and monoacetylaniline class weed killer herbicide MONSANTO CO (US) 1991-07-10 CN claimed
CN-1039949-A The protection of benzoic acid derivative class weed killer herbicide MONSANTO CO (US) 1990-02-28 CN claimed