Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10288448 | 0.81 | CYP2C19 (0.44) | ALDH1A1LMNAALOX15NPSR1CYP2C19 | |
| SCHEMBL27703020 | 0.78 | ALDH1A1 (0.39) | ALDH1A1LMNAALOX15NPSR1CYP2C19 | |
| Hydrochloric Acid SCHEMBL28340422 | 0.77 | AGTR1 (0.43) | TLR7AGTR1 | |
| SCHEMBL8556750 | 0.76 | HDAC6 (0.41) | ALDH1A1LMNAALOX15NPSR1TSHR | |
| SCHEMBL28334546 | 0.76 | TLR7 (0.38) | ALDH1A1ALOX15TLR7AGTR1 | |
| SCHEMBL14037790 | 0.73 | CYP2C19 (0.38) | ALDH1A1LMNAALOX15NPSR1CYP2C19 | |
| SCHEMBL31633747 | 0.73 | TLR7 (0.45) | ALDH1A1TLR7TBXAS1 | |
| SCHEMBL27553901 | 0.71 | ALDH1A1 (0.39) | ALDH1A1TLR7AGTR1 | |
| SCHEMBL13900377 | 0.69 | ALDH1A1 (0.41) | ALDH1A1LMNAALOX15NPSR1 | |
| SCHEMBL16268172 | 0.68 | MAPT (0.44) | ALDH1A1LMNAALOX15NPSR1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| US-5552420-A | TREATING PICORNAVIRAL INFECTIONS | STERLING WINTHROP INC. (US) | 1996-09-03 | — | — | US | disclosed |