Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 6/20 | 0.33 |
| ▸ | RXRB | P28702 | 6/20 | 0.33 |
| ▸ | RXRG | P48443 | 6/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553960 | 0.81 | SLC29A1 (0.59) | SLC29A1GAARXRARXRBRXRG | |
| SCHEMBL8557836 | 0.78 | SLC29A1 (0.43) | SLC29A1GAAMEN1LMNAKMT2A | |
| SCHEMBL8557838 | 0.78 | KCNK3 (0.35) | NR4A2RXRARXRBRXRGKCNK3 | |
| SCHEMBL8554772 | 0.73 | SLC29A1 (0.53) | SLC29A1NR4A2CYP3A4CYP2C19RXRA | |
| SCHEMBL8552619 | 0.73 | SLC29A1 (0.53) | SLC29A1NR4A2CYP3A4CYP2C19RXRA | |
| SCHEMBL8553498 | 0.69 | SLC29A1 (0.49) | SLC29A1NR4A2CYP3A4CYP2C19RXRA | |
| SCHEMBL8553599 | 0.69 | KDR (0.48) | NR4A2CYP3A4CYP2C19GAARXRA | |
| SCHEMBL8554766 | 0.66 | KDR (0.45) | SLC29A1NR4A2CYP3A4CYP2C19RXRA | |
| SCHEMBL8598990 | 0.66 | SLC29A1 (0.45) | SLC29A1NR4A2CYP3A4CYP2C19RXRA | |
| SCHEMBL18409631 | 0.65 | KCNH2 (0.49) | NR4A2CYP3A4CYP2C19RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | claimed |