Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553599 | 0.91 | KDR (0.48) | NPC1RAB9AALDH1A1KMT2AKDR | |
| SCHEMBL8553960 | 0.87 | SLC29A1 (0.59) | SLC29A1NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL8557576 | 0.83 | MEN1 (0.52) | SLC29A1ALDH1A1KMT2AOGAMEN1 | |
| SCHEMBL8554568 | 0.81 | KDR (0.58) | ALDH1A1KMT2AKDRMEN1TSHR | |
| SCHEMBL8557838 | 0.80 | KCNK3 (0.35) | ALDH1A1TSHRLMNAHTT | |
| SCHEMBL8556969 | 0.79 | REV1 (0.53) | ALDH1A1KMT2AOGAKDRMEN1 | |
| SCHEMBL8554274 | 0.79 | KDR (0.45) | NPC1RAB9AALDH1A1KDRGAA | |
| SCHEMBL8552619 | 0.79 | SLC29A1 (0.53) | SLC29A1KDRTSHRHPGDDRD4 | |
| SCHEMBL8553498 | 0.79 | SLC29A1 (0.49) | SLC29A1KDRTSHRHPGDDRD4 | |
| SCHEMBL8554772 | 0.79 | SLC29A1 (0.53) | SLC29A1KDRTSHRHPGDDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | claimed |
| EP-0582164-A1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | Bristol-Myers Squibb Company (US) | 1994-02-09 | — | — | EP | claimed |